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  • Hit identification, hit-to-lead, and lead optimization
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Speed

Break the speed barrier searching billions of available molecules

  • Ligand- and structure-based virtual screening
  • Molecular dynamics (MD) simulations
  • Affinity predictions
  • Quantum chemistry calculations
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  • Screen ultra-large scale compound databases
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  • Design & screen antibody libraries using NGS
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> 12B

3D conformer-expanded compounds from commercial vendors

> 2.2M

searchable protein binding sites

> 100K

docking- and MD-ready protein structures
Cadence Announces New Life Sciences Leadership
miniWebinar: Opening up the druggable universe one cryptic pocket at a time
Essentials of Computational Drug Discovery - Complimentary Access
New Year’s 2025 Fireside Chat with Anthony Nicholls
miniWebinar: Optimizing lead compounds with efficient binding free energy calculations
Resources

Glimpse the Future through News, Events, Webinars and more

News

Cadence Announces New Life Sciences Leadership

Cadence Molecular Sciences (OpenEye) (CMS)—a business unit of Cadence Design Systems, Inc. Corporate Vice President, Anthony Nicholls, PhD, has announced his retirement as of January, 2025.
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Webinar

miniWebinar: Opening up the druggable universe one cryptic pocket at a time

In our first miniWEBINAR of 2025 we were talking about a computational workflow to validate difficult-to-drug protein targets in "Opening up the druggable universe one cryptic pocket at a time" session presented by David LeBard, Head of Enhanced Sampling at OpenEye, Cadence Molecular Sciences,
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Webinar

Essentials of Computational Drug Discovery - Complimentary Access

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News

New Year’s 2025 Fireside Chat with Anthony Nicholls

Read now
Webinar

miniWebinar: Optimizing lead compounds with efficient binding free energy calculations

Read now
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